Tight Brain Checklist

Posted by Clark Venable on 2/11/2006

The anesthetist can have a significant impact on the operating conditions a neurosurgeon has to work with. One example is a situation where the surgeon (or anesthetist) notices the brain no longer appears relaxed but begins to get 'tight' within the craniotomy window. Rather that a knee-jerk response of further hyperventilating the patient and/or giving Mannitol, it is prudent to first consider possible causes as follows:

  1. Are the pressures controlled?
  2. Is the metabolic rate controlled?
  3. Are vasodilators in use?
  4. Are there any unexpected mass lesions?

Are the pressures controlled?

  • Arterial Pressure
  • pCO2
  • pO2 (remember that hypoxemia is a potent stimulus for cerebral vasodilation
  • Intrathoracic pressure
  • Airway pressure
  • Jugular venous pressure (includes external venous compression by C-spine collar or twill used to secure endotracheal tube)

Is the metabolic rate controlled?

  • Pain
  • Light anesthesia
  • Awareness
  • Seizures

Are vasodilators in use?

  • Potent agents (Isoflurane, Desflurane, Sevoflurane, Enflurane)
  • Nitroprusside
  • Nitroglycerine

Are there any unexpected mass lesions?

  • Pre-existing pneumocephalus exacerbated by nitrous oxide
  • Cerebral hemorrhage remote to the site of surgery

As taught to me by John Drummond, M.D. at UCSD

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