Sunday, November 20, 2005

Trial lawyers blocking avian flu bill

ATLA blocking avian flu bill:

" The Washington Post's Jeffrey Birnbaum reports: "Legislation that would pour billions of dollars into the production of vaccines against avian flu and other pandemic diseases is threatened by the trial lawyers' lobby, which objects to proposed limits on lawsuits against drug manufacturers. "

All in the name of protecting patients, I'm sure.

[Via PointOfLaw Forum]


EFF: Legal Guide for Bloggers

Electronic Frontier Foundation: Legal Guide for Bloggers

"The goal here is to give you a basic roadmap to the legal issues you may confront as a blogger, to let you know you have rights, and to encourage you to blog freely with the knowledge that your legitimate speech is protected."

[Via O'Reilly Radar]


More on pre-emptive positioning

A fellow anesthesiologist wrote a reply to my post about pre-emptive positioning with the following:

"We've started doing the same thing at my surgicenter. At first I thought it was pretty ballsy when one of my colleagues suggested that we do simple one level laminectomies under LMA general and induce in the prone position. But now that we've started it I am very comfortable with the idea."

I'm not ready to try this yet (do you want to be my first patient?). Lateral or semi-sitting to supine is a matter of seconds. Prone to supine would take significantly longer I believe. Other experiences?



Sunday, November 6, 2005

You Anesthesiologist Today Was...

I finally ordered my own business cards. I've had generic one available but always had to write in my own name (despite being with the group for well over two years) so decided it was time for an upgrade.

Picking the pattern was tough, but I decided on a tranquil image (that happens to be one of the MacOS X desktop images):

Rejected images included a dark tunnel with a light at the end, and anything with pearly gates.

This decision was evidence based (of course). Giving patients a business card before anesthesia increases their recall of your name to about 50% rather than the 10% that remember it without. It should also help them see they are being cared for by a physician. There's room on the back for 'anesthetic' and 'comments', too.



Thursday, November 3, 2005

Pre-emptive Patient Positioning

Many surgeries require the patient to be in a position other than supine (flat on their back) for the surgery to be done. Shoulder surgery, for example, is often done with the patient in a semi-sitting or 'beach chair' position. Certain hip surgeries are done with patients on their side as well. General anesthesia is induced with the patient supine, then people have to move the patient (who is now akin to a very heavy sack of potatoes) into the right position. It's time consuming, risks staff injury, and jeopardizes the airway. The few accidental extubations I've had have occurred when the patient was being moved. Does it have to be this way? If the case is amenable to an LMA, I think the answer is 'no.'

If I'm caring for a patient who will require a general anesthetic and an LMA would be suitable, I've taken to positioning the patient before induction of anesthesia. I then pre-oxygenate, perform an IV induction, and place the LMA. The OR staff and surgeons like it because a) it saves time and b) it saves their backs. I like it because there's no move during which my airway can potentially be compromised (and because it saves time and saves my back). There's a benefit to the patient, too. Namely, they can tell us while awake whether our positioning is comfortable for them. Is the axillary role in the right place? Do they need a pillow under their knees in? Is their bottom up against the back of the table in beach chair? Is their ear properly padded in the lateral position? Think Different (but always, Think Safe).



Saturday, October 15, 2005

Bird flu virus reported to resist Tamiflu

More popular press stories on drug resistance in bird flu:

"An avian influenza virus isolated from an infected Vietnamese girl has been determined to be resistant to the drug oseltamivir, the compound better known by its trade name Tamiflu, and the drug officials hope will serve as the front line of defense for a feared influenza pandemic. [Science Blog - Science News Stories]"

The New England Journal of Medicine has a recent free article summarizing our current state of knowledge titled Avian Influenza A (H5N1) Infection in Humans:

"High-level antiviral resistance to oseltamivir results from the substitution of a single amino acid in N1 neuraminidase (His274Tyr). Such variants have been detected in up to 16 percent of children with human influenza A (H1N1) who have received oseltamivir. Not surprisingly, this resistant variant has been detected recently in several patients with influenza A (H5N1) who were treated with oseltamivir."

This is not to say, however, that we have no other neuraminidase inhibitor tricks up our sleeves.


Sunday, October 9, 2005

The Cervical Cancer Vaccine

The Well Timed Period offers some (well referenced) Q's and A's about the cervical cancer vaccine:

"Q: Why do we need to vaccinate the population at large?
Q: Why are the vaccine trials focused on preferentially vaccinating young women?
Q: Why are HPV 16 and 18 the target of Merck's vaccine?
Q: Are the researchers working on the HPV vaccine aware of potential barriers to its acceptance?
"

She concludes:

" The HPV vaccine is an extremely significant development because it offers tremendous possibility in helping reduce the incidence of abnormal Pap smears, cervical cancer, and genital warts in the United States as well as worldwide. "

I Am A Propofologist

I've decided to change my title from 'Anesthesiologist' to the more descriptive 'Propofologist.' Maybe it's because I've been doing lots of sedation for colonoscopies and esophagogastroduodenoscopies (EGD) for which I use propofol/lidocaine only. When someone asks for anesthesia services, especially outside the operating room, what they're really asking for is someone who can give propofol to the point of loss of consciousness--hence the (new) term. Your heard it here first.



Monday, August 22, 2005

NYT: Sick and Scared, and Waiting, Waiting, Waiting

NYT: Sick and Scared, and Waiting, Waiting, Waiting

Medicine from the patient's side. A must read article no matter what specialty you're in.



Thursday, July 7, 2005

We are all Britons

[Shape of Days]



Friday, July 1, 2005

My take on the rumored iPhone

Podcasts. Everybody's talking about music, but I'd listen to podcasts (like this Make podcast on biodiesel). Any good medical podcasts out there yet?


Med Mal Costs 2004

Med Mal Costs 2004:

"Where is the most expensive place to defend oneself against malpractice in 2004? Florida is tops and Wyoming is the least expensive."

Hmmm. From the summary, it looks like my state (Pennsylvania) is 5th for costs incurred...

[Via PointOfLaw Forum]


How to survive a deposition

"Malpractice: How to survive a deposition"

"Be concise, be cool, be prepared, and don't try to outwit the plaintiff's attorney."

[Via Overlawyered]



Friday, June 17, 2005

Review: Chronic Stable Angina

The NEJM has a very nice review article titled Chronic Stable Angina.
"It is useful to classify therapeutic drugs into two categories: antianginal (anti-ischemic) agents and vasculoprotective agents. Although medications for angina are widely used, therapy to slow the progression of coronary artery disease, to induce the stabilization of plaque, or to do both is a newer concept and these forms of treatment are underprescribed."


Medical Simulation Weblog

I found a neat new weblog called SimBlog. Associated with the Society for Medical Simulation, it appears to be edited by Jeff Taekman, formerly of Penn State and the person I came to Hershey to work with. Jeff had moved to Duke by the time I arrived, and is now the Associate Dean for Technology in Education there.



Saturday, June 11, 2005

NEJM -- Two-Years after Endovascular Repair of Abdominal Aortic Aneurysms

Very interesting Dutch study on Two-Year Outcomes after Conventional or Endovascular Repair of Abdominal Aortic Aneurysms in the NEJM. This is the first study to look at prolonged survival (2 years) after placing a tube stent into a dilated abdominal aorta (aneurysm) to prevent rupture. We know that early survival is better with the stent vs. open repair. But what about after the first month? This study shows that after two years, the survival is about the same:

" The cumulative rates of aneurysm-related death were 5.7 percent for open repair and 2.1 percent for endovascular repair. This advantage of endovascular repair over open repair was entirely accounted for by events occurring in the perioperative period, with no significant difference in subsequent aneurysm-related mortality. "

To try to explain this, the authors discuss the following possibilities:

"There may be two possible explanations for the convergence of survival curves in our study. One is that patients who have survived the stress of open repair may be somewhat less likely to die in the first few months after surgery than patients who have undergone endovascular repair, since the latter group has not been subjected to a conventional surgical procedure.
...[snip]...
Another possible explanation for the convergence of survival curves is the failure of endovascular repair to prevent rupture of the aneurysm."

I wonder about a third possibility: did patients having an open repair make lifestyle change that those having the less stressful endovascular repair did not? I ask because one of the frustrations in taking care of patients with vascular disease is the extent to which they do NOT change their eating or smoking habits and so need to come back for yet another procedure at yet another time. The study lists baseline characteristics (55% smoked in the open group and 64% smoked in the endovascular repair group. Half in each group had hyperlipidemia), but no characteristics are given at the two year point. Can the lack of survival advantage after endovascular repair be explained by differences in rates of smoking, hyperlipidemia, and other risk factors at two years?

And thanks to the power of Google, I've sent the lead author an e-mail with just this question!

8: 00 A.M., the lead author writes back:

"We haven't studied that in this 2-year analysis but it is part of our long-term study."


Malpractice Insurance for Bariatric Surgeons Increasing

Other Perils of Overweight - New York Times:

" But after several years in which the surgery was seen as the last best hope by many obese people, a growing array of scientific data shows that the risks are greater than patients realized. One new study reported that almost one in 5 patients had complications after surgery. For one in 20 patients, the complications were serious, including heart attacks and strokes. Another recent study said the mortality rate for the most common type of bariatric surgery, gastric bypass, was one in 200 - a rate higher than for coronary angioplasty, which opens blocked heart vessels.

For thousands of patients, the weight-loss surgery has eliminated debilitating diseases and improved the quality of life. But the threat of malpractice lawsuits against doctors and hospitals, as well as the reluctance of health plans to cover the surgery costs, is creating difficulties for people now seeking treatment. "

The article points to an Annals of Internal Medicine article titled Meta-Analysis: Surgical Treatment of Obesity (Annals is another one of those nice free full-text journals).

[Via Common Good]

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